THE EFFECT OF ANTI-TUBERCULOSIS DRUGS AGAINST THE INFLAMMATION PROCESS OF THE DISEASE THROUGH ERYTHROCYTE SEDIMENTATION RATE TEST IN PUKESMAS TUMINTING, MANADO

Sumampouw, Jonas E. and Pasambo, Yourisna (2021) THE EFFECT OF ANTI-TUBERCULOSIS DRUGS AGAINST THE INFLAMMATION PROCESS OF THE DISEASE THROUGH ERYTHROCYTE SEDIMENTATION RATE TEST IN PUKESMAS TUMINTING, MANADO. 1 st International Conference on Medical Laboratory Technology (ICoMLT). pp. 1-6.

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Abstract

The general purpose of this study was to assess the progress of treatment on Tuberculosis (TB) patients through ESR examination while the specific purposes were to know the average of ESR examination results in both stages of treatment of TB Category 1 patients and to prove that there is a relationship between administered of anti-TB drugs against ESR on TB patient. The study design was cross-sectional with laboratory tests. Venous blood samples from 30 adult TB Patients that fulfilled inclusion criteria were examined for ESR. 13 patients were in the initial phase while 17 patients were in the continuation phase. Some samples were withdrawn when patients came to Health Center to seek treatment and some patients were taken by visiting their houses. The result of the study found that mean of ESR from each stage of treatment is different, from 21,5 mm/hour in the initial phase decreased to 11,35 mm/hour in the continuation phase. To assess the effect of anti-tuberculosis drugs on the inflammation process in each phase of treatment, statistical analysis was used using a correlation test. The correlation r-value was -0,457 with a p-value of 0,006 shows that there was a significant effect of administration of the anti-tuberculosis drugs in decreasing ESR in patients from initial phase to continuation phase. The study concludes that anti-tuberculosis drugs are effective in decreasing the inflammation process of tuberculosis.

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